The second pillar of Horizon Europe includes a challenge-based approach that will bring together resources and knowledge across different fields, technologies and disciplines, including social sciences and the humanities. This will cover activities from research to market with a new focus on innovation-related activities. Funding will focus on the following clusters: “Health”, “Culture, Creativity and Inclusive Society”, “Civil Security for Society”, “Digital, Industry & Space”, “Climate, Energy & Mobility”, “Food, Bioeconomy, Natural Resources, Agriculture & Environment”.