AIRC 2022 - Deciphering the molecular mechanisms driving the interplay between tumor-associated immune cells and cancer cells

Finanziato dalla Fondazione AIRC, Ministero della Salute

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Abstract

We aim to describe new pathways involved in immunoresistance, with particular attention to mast cells (MCs) and B cells as their role in tumorigenesis and CRC progression is largely obscure. Our contribution to the topic and the data generated will help to define new approaches and more personalized therapies against CRC.

A more complete understanding of the MC-B cell interactions in CRC, as well as their contribution to the establishment of a suppressive ME, will enhance and personalize therapeutic options and improve clinical outcomes.

 

Importo del progetto

Importo totale del progetto        Euro 557.700,00
Importo del progetto Uniud        Euro 557.700,00
Finanziamento Uniud                Euro 0

 

Durata

  • Dal 02/01/2023
  • Al 01/01/2028

 

Link

https://www.airc.it/ricercatori/i-nostri-ricercatori/carlo-ennio-michele-pucillo